Stem Cell Therapy in Neurological Disorders

Stem Cell Therapy in Neurological Disorders

Dr.Alok Sharma
M.S, M.Ch.
Director – NeuroGen Brain & Spine Institute, Navi Mumbai
Professor & Head –Department of Neurosurgery,
LTMG Hospital, Sion.
Consultant Neurosurgeon - Fortis Hospital, Mulund.

Dr. Alok Sharma is a renowned Neurosurgeon, Neuroscientist and Professor who brings with him extensive surgical expertise & experience in the areas of Neurosurgery, Neuroscience and Regenerative Medicine. He is doing pioneering work in the field of Stem cell therapy for neurological disorders. He has over 25 years of experience in the field of Neurosurgery and has several awards and recognitions to his name. He has authored 15 books and has over 100 scientific papers published in various medical journals.

NeuroGen Brain & Spine Institute which is one of the country’s first dedicated centre for Cell Therapy and NeuroRehabilitation was founded by Dr Alok Sharma. It is focused on treating patients with incurable neurological conditions. Its innovative and pioneering cell therapy gives new lease of life to patients  with Autism, Cerebral Palsy, Mental Retardation, Muscular Dystrophy, Spinal Cord Injury, Head Injury, Brain stroke and Other incurable neurological disorders. 

What is Stem Cell therapy and how does it help patients with incurable neurological disorders?

 
Stem cells are specialized cells that can convert into any type of tissue and they have the ability to reach and repair the damaged parts of our body. Stem cell therapy is a simple and effective treatment which is 100 % safe when autologous adult Stem cells are used. Statistics have shown that, after Stem cell therapy, over all 91% of patients with Autism have shown improvements in social relationships, emotional responses, speech, communication, behavior and hyperactivity. 96% of Stroke patients showed improved upper and lower limb activity, 82% of patients with Spinal Cord Injury showed better Muscle tone, trunk activity, balance and other activities of daily living. In Cerebral Palsy, 92% of treated patients showed improvement in oromoter/ speech, balance, upper limb and lower limb activity. In Muscular dystrophy, which is a progressive disease of the muscles, about 90% of the patients attain stabilization in their progression with improved function.


How do Stem cells work?

Stem cells work by releasing growth factors which have a regenerative effect on damaged tissue. They promote angiogenesis or increase in the blood supply of damaged tissue thereby helping in their repair process. They convert into the tissue/cell types in which they are implanted, thereby replacing non-functioning tissue.

What are the different types of Stem cells?
Allogenic Stem cells: These are the Stem cells taken from another person. For example embryonic Stem cells.
Autologous Stem cells: These are the Stem cells derived from the patient’s own body, such as bone marrow Stem cells from the hip bone. These are absolutely safe have no compatibility issue.

What conditions can be treated?
Several disease and injuries of the nervous system and musculoskeletal system that have no other treatment options can be potentially treated with Stem cell therapy. In children these include Autism, Cerebral Palsy, Mental Retardation, Muscular Dystrophy and in adults these includes Spinal Cord Injury, Brain Stroke, Motor Neuron Disease and Other Neurological Disorders.

How is the response to treatment assessed objectively?
Recent advances in modern imaging such as PET – CT scans/fMRI/high resolution MRIs’ have made it possible to assess changes in the brain, muscles and spinal cord. For eg.PET CT Scan of brain in children with autism shows that there are selective areas in the brain that are not functioning normally. Stem cell therapy has been shown to reverse this damage helping the child to maximize his level of independence.

 

What is the scientific basis of Stem Cell Therapy?
Extensive, ongoing research work published in various medical journals forms the basis of this therapy. This information can be found on www.Stemcellspublications.com, which has all the world literature as well as the 41 scientific articles and 9 books published by NeuroGen BSI. The first ever publication showing the safety and efficacy of Stem cell therapy in autism was published by NeuroGen BSI, showing the leadership of India in this field.

Contact: NeuroGen Brain & Spine Institute
Sector 40,Plot No 19,Opposite Rail Vihar,
Near Seawood Grand Central Station,
 Off Palm Beach Road, Nerul (W)
New Mumbai -400706.
Tel:022-41136565 /9920200400
Email- contact@neurogenbsi.com
Web: www.neurogenbsi.com